In this passage from Revelation 16, God commands seven angels to unleash His wrath upon Earth through vials, each bringing a catastrophic plague. The first angel's vial causes painful sores on those marked by the beast. The second transforms the sea into blood, killing all marine life within it. The third turns all freshwater sources into blood, symbolizing retribution for the blood of the saints and prophets. As these plagues unfold, an angel justifies these acts as righteous judgment. The fourth angel intensifies the sun's heat, scorching humanity, yet instead of repenting, people curse God, highlighting a stubborn refusal to acknowledge His power.